Dr. Carp's research group focuses on the development and clinical translation of light-based non-invasive sensing and imaging methods for disease detection and management. Major thrusts include the use of near-infrared spectroscopy and tomography as well as diffuse correlation spectroscopy to adv...
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Yi-Fen Yen
Over the past two decades, Dr. Yen has devoted herself to the development of advanced MRI techniques, for hyperpolarized metabolic imaging, cancer imaging and functional imaging in clinical and pre-clinical research. She is an MR physicist with >100 publications in peer-reviewed scientific jou...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
The Epigenetics of Aging: Understanding neurodegeneration at the gene transcription level
Over the past century, life expectancy has doubled. Consider for a moment the impact of this factoid on our interpretation of the aging brain. Prior to the 20thcentury – indeed, throughout nearly all of history – there was likely no evolutionary pressure for humans to live beyond reproductive age...
ISMRM Welcomes New President Larry Wald
The International Society for Magnetic Resonance in Medicine (ISMRM) concluded its Annual Meeting in Montreal, Canada, with the passing of the presidential gavel on Wednesday, 15 May 2019, to Larry Wald, director of the Magnetic Resonance - Physics & Instrumentation Group at the MGH Martinos ...
Magnetoencephalography Aids Diagnosis and Treatment of Epilepsy, Other Disorders
Originally used only for research purposes, magnetoencephalography (MEG) has been introduced into clinical care in recent decades. With applications in epilepsy already benefiting from its use, and still others on the horizon, the technique is helping to advance diagnosis and treatment for a rang...
Wellness Resources
To offer support to its staff and researchers, Partners, MGH, and several other groups have put together resources that address the challenges we may be facing in our day-to-day lives as we handle this unique situation. Here, we compile those resources & information to make it easier for you ...
The (Totally True) Legend of Thomas Witzel and the Ultrahigh-field MRI Quench
Sometimes we get the hero we need. In the summer of 2017, the 7T MRI scanner at the MGH Martinos Center suffered a quench: a sudden loss of superconductivity resulting in a complete loss of the scanner’s magnetic field. In short, it broke. Without a magnetic field, the instrument was inoperabl...
Students
The Martinos Center is home to full-time Ph.D. and Master’s students in a host of disciplines: from Physics and Chemistry to Biology, Neuroscience and Psychology. The breadth of research at the Center provides many opportunities for students to find a lab that suits their interests. You can learn...
Douglas Greve
Douglas Greve, PhD, has a passion for delivering cutting-edge tools to the neuroscience community. He joined the FreeSurfer team 20 years ago and has been developing neuroimaging software ever since. His career has offered him an exciting mixture of engineering, physics, software development and ...
Daphne Holt Receives MGH Research Scholars Award
The Martinos Center's Daphne Holt is among the distinguished investigators in the 2018 Class of MGH Research Scholars. She received the honor for her project "Altered neural mechanisms of personal space in schizophrenia: a novel biomarker of negative symptoms and treatment target." Schizophren...
Martinos Responds: Don Straney and the Charlestown Face Shield Project
Don Straney isn't slowing down during the COVID-19 pandemic. A staff electrical engineer with the Martinos Center's human imaging core, Straney is volunteering with two different projects responding to the crisis. With the Charlestown Face Shield Project, he is forming face shield visors to donat...
Why & How
The Why & How seminar series is designed to introduce research assistants, graduate students, and postdoctoral and clinical fellows - really, anyone who is interested - to the many tools used in the Center. These include software tools and most of the major imaging modalities wielded by Marti...
Magnetic Resonance Imaging
The Center's magnetic resonance imaging (MRI) facilities include the following. Large-bore MRI Systems * All subject bays are equipped with Blu-ray/DVD players for subject entertainment Bay 1: Siemens 3T MRI Skyra with 128ch receive capabilities and 2ch pTx This is a Siemens 3T Skyra wit...
Redeployment During the COVID-19 Pandemic
On Monday, April 6, as MGH prepared for the expected surge in COVID-19 patients, the hospital's leadership announced the likely redeployment of significant numbers of non-clinical workers. MGH had now entered the "all hands on deck" phase of the pandemic, where the need for additional support sta...
Moving Beyond Biopsy for Liver Fibrosis
Chronic liver disease is a growing health concern in the U.S. and around the world, with links to alcoholism, diabetes and even obesity. One of the early manifestations of the disease is fibrosis, an excessive buildup of scar tissue that results from repeated injury to the liver. While its effect...
The Secret Lives of Martinos Folk: Carol Barnstead and the Center’s cast of colorful characters
I have this theory that you need to be a character to work at the Martinos Center; you have to be a bit of an oddball, albeit in a fun, quirky kind of way. I’m not sure whether this is a prerequisite enforced during one of the hiring steps or is simply the result of some kind of self-selection pr...
Q&A: Susan Whitfield-Gabrieli on Managing Anxiety and Depression with Mindfulness-Based fMRI Neurofeedback
In a paper recently published in Molecular Psychiatry, Martinos affiliated faculty member Susan Whitfield-Gabrieli and colleagues describe a mindfulness-based fMRI neurofeedback approach they have developed and highlight its potential in treating adolescents with a history of anxiety and depressi...
The Center’s Eric Gale to Address Anemia of Chronic Disease in Project Funded by HMS Award
Martinos Center researcher Eric Gale, PhD, is a recipient of this year’s HMS Blavatnik Therapeutics Challenge Award (BTCA). The BTCA program is designed to accelerate the development of therapeutics within Harvard Medical School (HMS) and its affiliated hospitals, with the specific goal of produc...
The Neuroscience of Personal Space
We all have a need for personal space, the comfort zone we maintain around our bodies, implicitly entreating others not to encroach upon it. In recent years researchers have been probing the ways in which we regulate this space, looking at how and why our brains tell us when someone is simply ...