The Martinos Optics Research facilities consists of multiple separate lab facilities including 1) fiber optic and electronics fabrication and testing, 2) instrumentation system development and testing, 3) small animal studies, 4) optical physics labs with floating tables, and 5) human subject tes...
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Publications Updates
May 11, 2020 The presubiculum links incipient amyloid and tau pathology to memory function in older persons Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Neurology. 2020 May 5;94(18):e1916-e1928. doi: 10.1212/WNL.00...
Nanodiamond-enhanced MRI: A Dazzling New Approach to Imaging
Nanodiamonds – synthetic industrial diamonds only a few nanometers in size – have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well as for other uses. Thus far, options for imaging nanodiamonds have been li...
The Epigenetics of Aging: Understanding neurodegeneration at the gene transcription level
Over the past century, life expectancy has doubled. Consider for a moment the impact of this factoid on our interpretation of the aging brain. Prior to the 20thcentury – indeed, throughout nearly all of history – there was likely no evolutionary pressure for humans to live beyond reproductive age...
Optics Technologies Could Advance Neuromonitoring During Heart Surgery
A team of researchers at the MGH Martinos Center for Biomedical Imaging has reported an innovative light-based technique that could help reduce the incidence of neurological injury during aortic arch replacement and other cardiac surgeries. Deep hypothermic circulatory arrest (DHCA) is a techn...
Peter Caravan Promoted to Full Professor
The Center's Peter Caravan has been named Professor of Radiology at Harvard Medical School. Caravan is Director of a multidisciplinary and translational molecular imaging group at the Center (the Caravan Lab) and co-director of the Institute for Innovation in Imaging (I3) at Massachusetts Gene...
Risk, Resiliency in Aging Brain Focus of $33 Million Grant
A large study that investigates just what keeps our brains sharp as we age and what contributes to cognitive decline has been launched by Martinos Center researchers in collaboration with colleagues from Washington University School of Medicine in St. Louis, the University of Minnesota Medical Sc...
A New Role for Diffusion MRI in Treating Anxiety and Depression
Anxiety disorders and depression are widespread among adolescents in the U.S., affecting as many as one in four 13 to 18 year olds. Determining the best course of treatment can be difficult, though, as we still don’t fully understand the biology underlying them. Now, using cutting-edge brain i...
Bruce Fischl
Bruce Fischl, PhD, is a Professor of Radiology at Harvard Medical School and Director of the Laboratory for Computational Neuroimaging at the Martinos Center for Biomedical Imaging. A leader in the field of image processing and analysis, he has spearheaded the development of a range of innovative...
Advanced MRI of Spinal Cord Function Could Provide Important Information for the Treatment of Multiple Sclerosis
A team of investigators at the MGH Martinos Center for Biomedical Imaging and Vanderbilt University Medical Center has reported a new approach to measuring spinal cord function that could help in more accurately understanding the degree of spinal cord damage in relapsing-remitting multiple sclero...
Robert Savoy
Dr. Savoy received his academic training in applied mathematics at MIT (BS 1971; MS 1975) and experimental psychology at Harvard University (PhD 1980). This period included 10 years of work at Polaroid Corporation’s Vision Research Laboratory, after which he joined the newly formed Rowland Instit...
‘Pioneer Campfires’ Offer Stories of the Early Days of fMRI
Imagine sitting by a campfire, listening to trailblazers and other witnesses to key moments in the history of MRI as they casually recount the untold stories behind seminal papers or inventions. Attendees of the International Society for Magnetic Resonance in Medicine (ISMRM) 2019 Annual Meeting ...
Jason Stockmann
Jason Stockmann, PhD, is broadly interested in magnetic resonance imaging hardware and acquisition methods for improving data quality for both structural and functional imaging. He has worked on diverse MRI scanners ranging in field strength by two orders of magnitude, from low-field (80 mT) to u...
Chongzhao Ran
Chongzhao Ran, PhD, is an Associate Professor in Radiology at Massachusetts General Hospital and Harvard Medical School. He received a Master's degree in medicinal chemistry from China Pharmaceutical University and a PhD in medicinal chemistry from Shanghai Institute of Pharmaceutical Industry, C...
The Road to MPI
Functional MRI has proved a transformative technology, yielding previously unimaginable insights into the workings of the brain. But what if there were another approach, one with dramatically higher sensitivity, that could shed even more light on these mysteries? What might we learn then? Larry ...
Dara Manoach
Dr. Manoach is a clinically licensed neuropsychologist and an experimental psychologist by training. She has dedicated her career to understanding the neural basis and nature of fundamental cognitive deficits in neuropsychiatric disorders, particularly schizophrenia and autism. Although sleep pla...
Xin Yu
Xin Yu studied Neuroscience and Biophysics at New York University, USA. During his Ph.D. training in Dan Turnbull’s lab, he implemented Manganese-enhanced MRI to study the auditory midbrain plasticity and mid-hindbrain development. Meanwhile, he was trained by Dan Sanes to target the inferior col...
Ona Wu
The research goals of Dr. Wu's group are to improve the diagnosis, prognosis and management of patients with brain injury by quantifying and monitoring injury or recovery on an individual patient basis. The group focuses particularly on stroke, cardiac arrest and traumatic brain injury. Predictin...
Lab Site Directory
A1 Pain Imaging Lab Auditory Cognition Lab Brain Aging and Dementia (BAnD) Lab Brainstem Imaging Lab The Caravan Lab Center for Integrative Pain NeuroImaging (CIPNI) Cerebrovascular Aging and Spin Labeling Lab (CASL) Chemical Neuroscience Program Clinical Computational...
Christian Farrar
The Farrar group's research program is focused on the development of novel Magnetic Resonance molecular imaging contrast agents and methods and on the development of innovative Magnetic Resonance Imaging (MRI) methods for characterizing vascular structure and function. The tools being developed i...