In the waning months of 1979, the legendary Motown artist Stevie Wonder released an album called Stevie Wonder’s Journey Through "The Secret Life of Plants," the soundtrack to the documentary film The Secret Life of Plants. Equal parts frustrating and strangely compelling, and notably using some ...
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Radiology Diversity, Equity and Inclusion Research Subcommittee
The Radiology Diversity, Equity and Inclusion Research Subcommittee at the Martinos Center has gathered a number of resources to help promote diversity, equity and inclusion at the Center and elsewhere. Youth Programs Following is a list of programs through which Martinos faculty and other rese...
Sava Sakadzic
Dr. Sakadzic obtained his Ph.D. with Dr. Lihong Wang at Texas A&M University and completed his postdoctoral training with Dr. David Boas at the Massachusetts General Hospital. His group is developing state-of-the-art optical microscopy imaging technologies and utilizing them to better understand ...
AMA @ Martinos: Jon Polimeni
On Thursday, June 23, the Martinos Center's Jon Polimeni will deliver a keynote lecture at the 2022 meeting of the Organization of Human Brain Mapping (OHBM) in Glasgow, Scotland. In advance of the lecture, Jon is an all-around fascinating guy, so we were thrilled when he agreed to submit to an "...
Courses in the Harvard-MIT Health Sciences and Technology Program
HST.583/9.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis [Lecture: Mon & Wed 3pm, Lab: Mon 12.30pm-2pm, Recitation: Wed 2pm] Provides background necessary for designing, conducting, and interpreting fMRI studies in the human brain. Covers in depth the physics of ...
Ultrahigh-field MRI Tracks Development of Cortical Lesions in Multiple Sclerosis Patients
The development of lesions in the brain’s cortical gray matter is a strong predictor of neurological disability for people with multiple sclerosis (MS), according to a study reported today in the journal Radiology. The findings suggest a role for ultrahigh-field MRI in monitoring the progression ...
Deep Learning Algorithm Can Measure Disease Severity and Change on a Continuous Spectrum
Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
Nutrition and Brain Growth in the Developing World
The aging pickup truck bounces along a dirt road somewhere outside Bissora, one of the larger towns in the Oio region of the West African nation of Guinea-Bissau. The road, a major thoroughfare in the region, is pocked with holes. The rest of the year these would be deep and dusty. But it’s July ...
The Radiochemistry Team, and Everything That Doesn’t Go Wrong
PET-MR, a multimodality imaging technique that pairs the whole-body functional imaging of positron emission tomography (PET) with the local anatomic detail and morphological information of magnetic resonance (MR) imaging, shows great potential for clinical application. We still don’t know exactly...
Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
A New Role for Diffusion MRI in Treating Anxiety and Depression
Anxiety disorders and depression are widespread among adolescents in the U.S., affecting as many as one in four 13 to 18 year olds. Determining the best course of treatment can be difficult, though, as we still don’t fully understand the biology underlying them. Now, using cutting-edge brain i...
Optical Imaging
The Martinos Optics Research facilities consists of multiple separate lab facilities including 1) fiber optic and electronics fabrication and testing, 2) instrumentation system development and testing, 3) small animal studies, 4) optical physics labs with floating tables, and 5) human subject tes...
Nanodiamond-enhanced MRI: A Dazzling New Approach to Imaging
Nanodiamonds – synthetic industrial diamonds only a few nanometers in size – have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well as for other uses. Thus far, options for imaging nanodiamonds have been li...
Imaging Services
The backbone of the Martinos Center is the Martinos Technology Core, comprising Imaging and Computational Core resources. The Imaging Cores include the MRI, MEG and Optical Imaging Cores, with an extensive and expanding inventory of state-of-the-art imaging facilities and equipment, including rel...
Steven Stufflebeam
Steven Stufflebeam, MD, translates basic science and advanced imaging technology into everyday clinical practice. His laboratory aims to improve the health care for patients with epilepsy, schizophrenia, brain tumors and hearing impairments. His training is in biomedical engineering, mathematics ...
Xin Yu
Xin Yu studied Neuroscience and Biophysics at New York University, USA. During his Ph.D. training in Dan Turnbull’s lab, he implemented Manganese-enhanced MRI to study the auditory midbrain plasticity and mid-hindbrain development. Meanwhile, he was trained by Dan Sanes to target the inferior col...
Q&A: Susan Whitfield-Gabrieli on Managing Anxiety and Depression with Mindfulness-Based fMRI Neurofeedback
In a paper recently published in Molecular Psychiatry, Martinos affiliated faculty member Susan Whitfield-Gabrieli and colleagues describe a mindfulness-based fMRI neurofeedback approach they have developed and highlight its potential in treating adolescents with a history of anxiety and depressi...
Magnetic Resonance Imaging
The Center's magnetic resonance imaging (MRI) facilities include the following. Large-bore MRI Systems * All subject bays are equipped with Blu-ray/DVD players for subject entertainment Bay 1: Siemens 3T MRI Skyra with 128ch receive capabilities and 2ch pTx This is a Siemens 3T Skyra wit...
Nicole Zurcher Wimmer
Nicole Zürcher, PhD, is Assistant Professor of Radiology at Harvard Medical School and Massachusetts General Hospital (MGH), a faculty member at the A. A. Martinos Center for Biomedical Imaging and the Director of Human Imaging in the Chemical Neuroscience Program. She is Faculty Associate at the...
Albert Kim
I am an oncologist with interests in using machine learning and Omics to develop precision-based treatment paradigms and study therapuetic resistance. My laboratory efforts leverage Omics-based techniques, medical imaging (e.g., radiology, pathology), and machine learning to define and target ge...