Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
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The Radiochemistry Team, and Everything That Doesn’t Go Wrong
PET-MR, a multimodality imaging technique that pairs the whole-body functional imaging of positron emission tomography (PET) with the local anatomic detail and morphological information of magnetic resonance (MR) imaging, shows great potential for clinical application. We still don’t know exactly...
The Secret Lives of Martinos Folk: Skating to the Roller Derby World Cup
Eszter Boros is no stranger to sports. As a teenager in Switzerland she played tennis competitively, advancing several times to the finals in the national junior championships. And even after giving this up to focus on her studies in chemistry, she continued to stay active—running, cycling and ev...
Sara Lazar
Sara W. Lazar, PhD, is an Associate Researcher in the Psychiatry Department at Massachusetts General Hospital and an Assistant Professor in Psychology at Harvard Medical School. The focus of her research is to elucidate the neural mechanisms underlying the beneficial effects of yoga and meditatio...
A New Optical Imaging Tool to Visualize Disease Through ‘Multiplexing’
A team of investigators at the MGH Martinos Center for Biomedical Imaging has developed a tool that will allow researchers to measure multiple biological components or processes at the same time, opening up a host of applications, especially related to the study of disease. They describe the tool...
Tweets From the Front Lines
In the past few weeks, we've seen a shift in the Martinos Center's Twitter feed. Usually teeming with tweets about the latest research, upcoming conferences and occasionally the antics of someone's adorable dog, the feed is now, unsurprisingly, dominated by updates about COVID-19 and the medical ...
New Portable Scanner to Bring MRI to the Patient
A team of researchers in the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has developed a low-cost, portable MRI scanner, reporting the device in the journal Nature Biomedical Engineering on November 23. In a recent conversation, lead author Clarissa Zimmerman Cooley g...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
Study Identifies Signs of Repeated Blast-Related Brain Injury in Active-Duty United States Special Operations Forces
United States (US) Special Operations Forces (SOF) personnel are frequently exposed to explosive blasts during training and combat. However, the effects of repeated blast exposure on the brain health of SOF personnel are unclear, and there is currently no diagnostic test that can detect brain inj...
Magnetoencephalography Aids Diagnosis and Treatment of Epilepsy, Other Disorders
Originally used only for research purposes, magnetoencephalography (MEG) has been introduced into clinical care in recent decades. With applications in epilepsy already benefiting from its use, and still others on the horizon, the technique is helping to advance diagnosis and treatment for a rang...
The First In Vivo Imaging Agent for Electrical Signaling in the Heart
Reliable and accurate functioning of the heart is vital for health and well-being. According to the World Health Organization, cardiovascular disease contributes to one third of all deaths worldwide. Unfortunately, currently used diagnostic methods are insufficient for early detection of the risk...
Bruce Rosen to Be Inducted Into National Academy of Inventors
Bruce Rosen, director of the MGH Martinos Center for Biomedical Imaging, has been elected as a Fellow of the National Academy of Inventors (NAI). He was chosen for induction, according to a statement by the NAI Fellows Selection Committee, because he has “demonstrated a highly prolific spirit ...
The Road to MPI
Functional MRI has proved a transformative technology, yielding previously unimaginable insights into the workings of the brain. But what if there were another approach, one with dramatically higher sensitivity, that could shed even more light on these mysteries? What might we learn then? Larry ...
Thomas Deisboeck
Tom Deisboeck has spent over 25 years in life sciences research. He holds an MD (Dr. med) from the Technical University of Munich as well as an MBA from Massachusetts Institute of Technology (MIT). Dr. Deisboeck is an Associate Professor of Radiology (PT) at Massachusetts General Hospital and Har...
The Neuroscience of Personal Space
We all have a need for personal space, the comfort zone we maintain around our bodies, implicitly entreating others not to encroach upon it. In recent years researchers have been probing the ways in which we regulate this space, looking at how and why our brains tell us when someone is simply ...
All in a Day’s Work: Veronica Clavijo Jordan on tackling cancer and crowdfunding molecular imaging research
As a child in La Paz, Bolivia, Veronica Clavijo Jordan was intrigued by science and medicine. “I used to love astronomy and biology,” she says. “I particularly remember loving the biology classes where we had lab and learned about anatomy.” Today, as an instructor in the MGH Martinos Center in Ch...
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Early Screening of ASD With a New Eye-tracking Paradigm
Studies have shown that early diagnosis and intervention significantly impact the prognosis of individuals with autism spectrum disorder (ASD): the earlier the detection and diagnosis, the better the prognosis and functional status later in life. Currently, the average age of diagnosis is approxi...
The Secret Lives of Martinos Folk: Carol Barnstead and the Center’s cast of colorful characters
I have this theory that you need to be a character to work at the Martinos Center; you have to be a bit of an oddball, albeit in a fun, quirky kind of way. I’m not sure whether this is a prerequisite enforced during one of the hiring steps or is simply the result of some kind of self-selection pr...
The Epigenetics of Aging: Understanding neurodegeneration at the gene transcription level
Over the past century, life expectancy has doubled. Consider for a moment the impact of this factoid on our interpretation of the aging brain. Prior to the 20thcentury – indeed, throughout nearly all of history – there was likely no evolutionary pressure for humans to live beyond reproductive age...