What if you held a clinical trial and nobody came? While plenty of patients are eager to participate, researchers often have difficulty reaching their target enrollments for clinical trials, the goal of which is to determine the safety and efficacy of new drugs or therapies before they are bro...
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The Secret Lives of Martinos Folk: Fighting Stereotypes of Women in Islam, One Karate Kick at a Time
Zeynab Alshelh has practiced karate since she was a young child growing up in Australia. For much of the time she has been involved with the sport, she has focused her efforts on the discipline known as shadow fighting, or Kata. Kata comprises a pre-arranged pattern of movements—kicks and punches...
New Portable Scanner to Bring MRI to the Patient
A team of researchers in the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has developed a low-cost, portable MRI scanner, reporting the device in the journal Nature Biomedical Engineering on November 23. In a recent conversation, lead author Clarissa Zimmerman Cooley g...
National Working Group Releases Landmark Ethical Guidance for New Portable MRI Brain Research
MRI has transformed neuroscience research over the past 50 years, but research participants have had to travel to the scanner. With the advent of highly portable magnetic resonance imaging (pMRI), including pioneering work at the Martinos Center, the scanner will now come to them. This portable t...
Molecular Imaging and the ‘Martinos Galaxy’: Jacob Hooker shows us the stars
The Martinos Center’s Jacob Hooker is standing in front of a crowded room in a gleaming building in Boston’s Seaport District. On a screen above him is an image with seemingly countless circles of different colors and sizes. Big green ones. Small blue ones. And so on. He refers to the image as...
Deep Learning Algorithm Can Measure Disease Severity and Change on a Continuous Spectrum
Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
The Radiochemistry Team, and Everything That Doesn’t Go Wrong
PET-MR, a multimodality imaging technique that pairs the whole-body functional imaging of positron emission tomography (PET) with the local anatomic detail and morphological information of magnetic resonance (MR) imaging, shows great potential for clinical application. We still don’t know exactly...
Meet Nilson Fernandes, the New Operations Director for the Martinos Center for Biomedical Imaging
This week, the Center welcomes a new member to the Martinos community: Nilson Fernandes, MHM, who will oversee operations of the Center's always expanding imaging core. He is the first person to occupy the newly created position of Operations Director. In this brief Q&A, Nilson tells us ab...
Hsiao-Ying Wey Receives 2016 New Investigator Award in Alzheimer’s Disease
The American Federation for Aging Research (AFAR) has awarded Hsiao-Ying (Monica) Wey, PhD, an investigator in the MGH Martinos Center and assistant professor at Harvard Medical School,with a 2017 New Investigator Award in Alzheimer’s Disease. The program is funded by The Rosalinde and Arthur ...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
Early Screening of ASD With a New Eye-tracking Paradigm
Studies have shown that early diagnosis and intervention significantly impact the prognosis of individuals with autism spectrum disorder (ASD): the earlier the detection and diagnosis, the better the prognosis and functional status later in life. Currently, the average age of diagnosis is approxi...
Matt Rosen and Colleagues’ Journey Through the Secret Life of Plants
In the waning months of 1979, the legendary Motown artist Stevie Wonder released an album called Stevie Wonder’s Journey Through "The Secret Life of Plants," the soundtrack to the documentary film The Secret Life of Plants. Equal parts frustrating and strangely compelling, and notably using some ...
‘Martinnovate’ Seminar Series Boosts Innovation at Martinos
The Martinos Center has always been a hotbed of entrepreneurship. Over the years, innumerable investigators and staff have launched companies seeking to commercialize products they have developed as part of their research. A new seminar series in the center aims to support this entrepreneuria...
The Martinos Center’s Got Talent!
On Wednesday, January 11, the MGH Martinos Center for Biomedical Imaging will stage its first-ever talent show, aptly titled: "The Martinos Center's Got Talent!" The event will showcase the many, varied talents of folks from across the center, from accordion playing to ballroom dancing, from stan...
20 Years of FreeSurfer
It’s a sunny day in Southern California and the developers of FreeSurfer—a suite of software tools for the analysis of neuroimaging data—are preparing for a training session to introduce scientists to the many benefits of the package. To help the scientists find the classroom they have hung “Free...
Advanced MRI of Spinal Cord Function Could Provide Important Information for the Treatment of Multiple Sclerosis
A team of investigators at the MGH Martinos Center for Biomedical Imaging and Vanderbilt University Medical Center has reported a new approach to measuring spinal cord function that could help in more accurately understanding the degree of spinal cord damage in relapsing-remitting multiple sclero...
ISMRM Welcomes New President Larry Wald
The International Society for Magnetic Resonance in Medicine (ISMRM) concluded its Annual Meeting in Montreal, Canada, with the passing of the presidential gavel on Wednesday, 15 May 2019, to Larry Wald, director of the Magnetic Resonance - Physics & Instrumentation Group at the MGH Martinos ...
Martinos Responds: ‘Community Help’ Website Brings People Together During a Time of Crisis
As healthcare challenges stemming from the COVID-19 pandemic continue to mount, and patient care and hospital operations schedules grow increasingly busy, many direct care providers are finding ineeds t difficult to keep up with needs at home—grocery shopping, pet care or any number of other resp...
20+20 Vision: 40 Years on the Cutting Edge of Science and Care
We are thrilled to announce the publication of 20+20 Vision: 40 Years on the Cutting Edge of Science and Care, a Martinos Center coffee table book. In 1980, a scrappy group of researchers at Massachusetts General Hospital banded together to explore the potential of a recently introduced techno...
Publications Updates
May 11, 2020 The presubiculum links incipient amyloid and tau pathology to memory function in older persons Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Neurology. 2020 May 5;94(18):e1916-e1928. doi: 10.1212/WNL.00...