This year, some 78,000 primary brain and other central nervous system (CNS) cancers will be diagnosed in the US alone. Researchers are actively developing new therapies for glioma, the most common type of primary brain tumor, but challenges remain in assessing whether patients are responding to t...
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Nutrition and Brain Growth in the Developing World
The aging pickup truck bounces along a dirt road somewhere outside Bissora, one of the larger towns in the Oio region of the West African nation of Guinea-Bissau. The road, a major thoroughfare in the region, is pocked with holes. The rest of the year these would be deep and dusty. But it’s July ...
Deep Learning Algorithm Can Measure Disease Severity and Change on a Continuous Spectrum
Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
Annual Fund
Thank you for your interest in the Annual Fund. Each year we rely on the generosity of friends of the Center to generously contribute to the Annual Fund. Gifts to the Annual Fund help provide funding to the best and brightest researchers to explore novel areas of research. Your financial support ...
Advanced MRI of Spinal Cord Function Could Provide Important Information for the Treatment of Multiple Sclerosis
A team of investigators at the MGH Martinos Center for Biomedical Imaging and Vanderbilt University Medical Center has reported a new approach to measuring spinal cord function that could help in more accurately understanding the degree of spinal cord damage in relapsing-remitting multiple sclero...
Fuyixue Wang
Dr. Wang is an Assistant Professor of Radiology at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS). She obtained her PhD degree from MIT in the Harvard-MIT Health Sciences and Technology department, receiving interdisciplinary training in electrical engineering, medical phys...
Nanodiamond-enhanced MRI: A Dazzling New Approach to Imaging
Nanodiamonds – synthetic industrial diamonds only a few nanometers in size – have recently attracted considerable attention because of the potential they offer for the targeted delivery of vaccines and cancer drugs as well as for other uses. Thus far, options for imaging nanodiamonds have been li...
A New Role for Diffusion MRI in Treating Anxiety and Depression
Anxiety disorders and depression are widespread among adolescents in the U.S., affecting as many as one in four 13 to 18 year olds. Determining the best course of treatment can be difficult, though, as we still don’t fully understand the biology underlying them. Now, using cutting-edge brain i...
Q&A: Susan Whitfield-Gabrieli on Managing Anxiety and Depression with Mindfulness-Based fMRI Neurofeedback
In a paper recently published in Molecular Psychiatry, Martinos affiliated faculty member Susan Whitfield-Gabrieli and colleagues describe a mindfulness-based fMRI neurofeedback approach they have developed and highlight its potential in treating adolescents with a history of anxiety and depressi...
Lisa Feldman Barrett
Lisa Feldman Barrett, PhD, is University Distinguished Professor of Psychology and Director of the Interdisciplinary Affective Science Laboratory (IASLab) at Northeastern University. She also holds research appointments in the Psychiatric Neuroimaging Program in the Department of Psychiatry and a...
Ultrahigh-field MRI Tracks Development of Cortical Lesions in Multiple Sclerosis Patients
The development of lesions in the brain’s cortical gray matter is a strong predictor of neurological disability for people with multiple sclerosis (MS), according to a study reported today in the journal Radiology. The findings suggest a role for ultrahigh-field MRI in monitoring the progression ...
The Radiochemistry Team, and Everything That Doesn’t Go Wrong
PET-MR, a multimodality imaging technique that pairs the whole-body functional imaging of positron emission tomography (PET) with the local anatomic detail and morphological information of magnetic resonance (MR) imaging, shows great potential for clinical application. We still don’t know exactly...
Risk, Resiliency in Aging Brain Focus of $33 Million Grant
A large study that investigates just what keeps our brains sharp as we age and what contributes to cognitive decline has been launched by Martinos Center researchers in collaboration with colleagues from Washington University School of Medicine in St. Louis, the University of Minnesota Medical Sc...
Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
A New Optical Imaging Tool to Visualize Disease Through ‘Multiplexing’
A team of investigators at the MGH Martinos Center for Biomedical Imaging has developed a tool that will allow researchers to measure multiple biological components or processes at the same time, opening up a host of applications, especially related to the study of disease. They describe the tool...
Anand Kumar
Dr. Kumar's research is focused on development and translation of novel biomedical optical techniques for preclinical and clinical applications. He has more than 15 years of experience in theory, modeling and experimental aspects of biological optical imaging. Over the past decade, his group has ...
Computational Services
Computing Facilities The Center’s IT infrastructure consists of over 400 CentOS Linux workstations and 150 Windows and Macintosh desktops in offices and labs owned by individual research groups. There is a server farm with over 50 Linux servers that handles central storage, email, web, print, s...
‘It’s All in the Eyes’: The role of the amygdala in the experience and perception of fear
Researchers have long believed that the amygdala, an almond-shaped structure in the brain, is central to the experience and perception of fear. Studies initiated in the 1990s of a patient with a rare condition affecting the amygdala initially seemed to support this conclusion. However, as the MGH...
MGB Radiology Research Celebration 2023
In 2023, the joint departments of Radiology Research at Massachusetts General Hospital and Brigham and Women's Hospital seek to recognize and support the accomplishments of our outstanding research faculty. We are immensely appreciative of the quality and quantity of their work. The annual Rad...
Christopher Bridge
Dr Bridge is trained as an engineer, with MEng (Distinction) and DPhil degrees from the University of Cambridge and University of Oxford, respectively. He has worked in the area of medical image analysis for nearly a decade. His work on his doctoral thesis involved the development of a system for...