Functional MRI has proved a transformative technology, yielding previously unimaginable insights into the workings of the brain. But what if there were another approach, one with dramatically higher sensitivity, that could shed even more light on these mysteries? What might we learn then? Larry ...
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Deep Learning Offers Quantitative Means of Monitoring Disease Progression in Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is an eye disorder affecting roughly two-thirds of premature infants weighing less than 250 g at birth and one of the leading causes of childhood blindness worldwide. Historically, clinical diagnosis of ROP has been subjective, resulting in considerable variabilit...
Center for Mesoscale Mapping
Brain science tools have advanced in several distinct directions. Advanced tools in molecular biology now allow neuroscientists to study distinct patterns of gene expression in individual neural cells, leading to the potential for a comprehensive atlas of cell types. In parallel, tools that allow...
Imaging Services
The backbone of the Martinos Center is the Martinos Technology Core, comprising Imaging and Computational Core resources. The Imaging Cores include the MRI, MEG and Optical Imaging Cores, with an extensive and expanding inventory of state-of-the-art imaging facilities and equipment, including rel...
Artificial Intelligence Improves Treatment Monitoring in Patients with Glioma
This year, some 78,000 primary brain and other central nervous system (CNS) cancers will be diagnosed in the US alone. Researchers are actively developing new therapies for glioma, the most common type of primary brain tumor, but challenges remain in assessing whether patients are responding to t...
Bastien Guerin
Dr. Guerin's research focuses on MRI (and to some extent PET) technology development and translation to neuro-imaging to help better understand the human brain. He has several areas of specialization: (i) Modeling and optimization of radio-frequency (RF) and gradient MR sub-systems. Dr. Geurin's...
Estimating Tumor Boundaries in Cancer Surgery With Fluorescence Lifetime Imaging
Cancer is the second leading cause of death in the United States, with an estimated 1,762,450 new cases diagnosed and 606,880 deaths in 2019 alone. While important advances have been made in the development of treatments for cancer, including surgery, a number of challenges remain. Not least: sur...
Understanding Eye-contact Avoidance in People With Autism
Individuals with autism spectrum disorder (ASD) often have difficulty looking others in the eyes. This is typically interpreted as a sign of social and personal indifference, but self-reports from people with autism suggests otherwise. Many say that looking others in the eye is uncomfortable or s...
Ilknur Ay
Dr. Ay is an Assistant Professor at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital and Harvard Medical School. She has a broad background in vascular pharmacology with fellowship training in neuroscience at the Massachusetts General Hospital. Dr. Ay’s main researc...
Jyrki Ahveninen
Dr. Ahveninen's mission is to apply novel and improved techniques to achieve more accurate estimates of human brain function than previously achieved. His work focuses on neuroimaging of human auditory system, auditory working memory and higher-order auditory cognition using techniques including ...
Anand Kumar
Dr. Kumar's research is focused on development and translation of novel biomedical optical techniques for preclinical and clinical applications. He has more than 15 years of experience in theory, modeling and experimental aspects of biological optical imaging. Over the past decade, his group has ...
Optical Imaging
The Martinos Optics Research facilities consists of multiple separate lab facilities including 1) fiber optic and electronics fabrication and testing, 2) instrumentation system development and testing, 3) small animal studies, 4) optical physics labs with floating tables, and 5) human subject tes...
Martinos Collaborators and Alum Receive 2024 Kavli Prize in Neuroscience
Congratulations to Nancy Kanwisher, PhD, Winrich Freiwald, PhD, and Doris Ying Tsao, PhD, on their receipt of the 2024 Kavli Prize in Neuroscience! Established in 2008 by Norwegian-American entrepreneur and philanthropist Fred Kavli, Kavli Prizes recognize innovative research in astrophysics, nan...
Karl Helmer
Karl Helmer, PhD, maintains research interests in several areas: (1) the creation of data management and sharing infrastructure; (2) the development of imaging protocols for multi-site MR imaging-based studies; (3) the creation of quality control and assessment software for MRI data; and (4) deve...
Changning Wang
Changning Wang, PhD, has a unique and broad background in molecular imaging, medicinal chemistry, pharmaceutical sciences and neuroscience. After finishing his doctoral studies, he joined Martinos Center for Biomedical Imaging as a research fellow and later as a trainee in the Harvard/MGH Nuclear...
A New Role for Diffusion MRI in Treating Anxiety and Depression
Anxiety disorders and depression are widespread among adolescents in the U.S., affecting as many as one in four 13 to 18 year olds. Determining the best course of treatment can be difficult, though, as we still don’t fully understand the biology underlying them. Now, using cutting-edge brain i...
Optics Technologies Could Advance Neuromonitoring During Heart Surgery
A team of researchers at the MGH Martinos Center for Biomedical Imaging has reported an innovative light-based technique that could help reduce the incidence of neurological injury during aortic arch replacement and other cardiac surgeries. Deep hypothermic circulatory arrest (DHCA) is a techn...
Byung Hee Yoo
Dr. Byung Hee Yoo's expertise lies in “theranostic cancer imaging." His research has focused on quantitative visualization of biological/physiological events. Since reporting the first peptidyl MR contrast agents, he has developed a wide spectrum of additional imaging probes for the quantitation ...
Pain Neuroimaging Night Spotlights Cutting-edge Imaging Technologies
During the 2018 World Congress on Pain in Boston last week, the Martinos Center showcased the latest advances in research into pain and the state-of-the-art technologies that make the research possible. Sponsored by the International Association for the Study of Pain (IASP), the World Congress...
New Bedside MRI Scanner Inspired by Martinos Center Research
Fundamental research by Professor Matthew Rosen, Director of the Low-Field Imaging Laboratory in the MGH Martinos Center, contributed to the early development of a new portable MRI scanner by Hyperfine Research Inc. The potentially game-changing technology will be introduced this week at the Amer...