The Martinos Center’s Jacob Hooker is standing in front of a crowded room in a gleaming building in Boston’s Seaport District. On a screen above him is an image with seemingly countless circles of different colors and sizes. Big green ones. Small blue ones. And so on. He refers to the image as...
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The Secret Lives of Martinos Folk: Kevin Dowling, Bagpiper in the Big City
Here is something of an unavoidable fact: If you play the Highland bagpipes you are going to draw a crowd, even if you aren’t actually looking for an audience. Just ask Kevin Dowling, a clinical research coordinator in the Brain Genomics Laboratory at the MGH Martinos Center for Biomedical Ima...
Deep Learning Algorithm Can Measure Disease Severity and Change on a Continuous Spectrum
Clinicians often use imaging to evaluate both the severity and progression of disease, in many cases by assigning severity to one of several categories based on the imaging findings and seeing whether and how the classification changes on follow-up. This approach can have its limits, though. B...
The Radiochemistry Team, and Everything That Doesn’t Go Wrong
PET-MR, a multimodality imaging technique that pairs the whole-body functional imaging of positron emission tomography (PET) with the local anatomic detail and morphological information of magnetic resonance (MR) imaging, shows great potential for clinical application. We still don’t know exactly...
Hsiao-Ying Wey Receives 2016 New Investigator Award in Alzheimer’s Disease
The American Federation for Aging Research (AFAR) has awarded Hsiao-Ying (Monica) Wey, PhD, an investigator in the MGH Martinos Center and assistant professor at Harvard Medical School,with a 2017 New Investigator Award in Alzheimer’s Disease. The program is funded by The Rosalinde and Arthur ...
Meet Nilson Fernandes, the New Operations Director for the Martinos Center for Biomedical Imaging
This week, the Center welcomes a new member to the Martinos community: Nilson Fernandes, MHM, who will oversee operations of the Center's always expanding imaging core. He is the first person to occupy the newly created position of Operations Director. In this brief Q&A, Nilson tells us ab...
Early Screening of ASD With a New Eye-tracking Paradigm
Studies have shown that early diagnosis and intervention significantly impact the prognosis of individuals with autism spectrum disorder (ASD): the earlier the detection and diagnosis, the better the prognosis and functional status later in life. Currently, the average age of diagnosis is approxi...
With New PET Probe, Researchers Image Fibrosis of the Lungs
The MGH Martinos Center's Pauline Désogère and colleagues have described a new positron emission tomography (PET) probe that can help to advance noninvasive diagnosis of pulmonary fibrosis. Reported in a Science Translational Medicine paper published online today, the probe enables detection and ...
Matt Rosen and Colleagues’ Journey Through the Secret Life of Plants
In the waning months of 1979, the legendary Motown artist Stevie Wonder released an album called Stevie Wonder’s Journey Through "The Secret Life of Plants," the soundtrack to the documentary film The Secret Life of Plants. Equal parts frustrating and strangely compelling, and notably using some ...
Advanced MRI of Spinal Cord Function Could Provide Important Information for the Treatment of Multiple Sclerosis
A team of investigators at the MGH Martinos Center for Biomedical Imaging and Vanderbilt University Medical Center has reported a new approach to measuring spinal cord function that could help in more accurately understanding the degree of spinal cord damage in relapsing-remitting multiple sclero...
20 Years of FreeSurfer
It’s a sunny day in Southern California and the developers of FreeSurfer—a suite of software tools for the analysis of neuroimaging data—are preparing for a training session to introduce scientists to the many benefits of the package. To help the scientists find the classroom they have hung “Free...
ISMRM Welcomes New President Larry Wald
The International Society for Magnetic Resonance in Medicine (ISMRM) concluded its Annual Meeting in Montreal, Canada, with the passing of the presidential gavel on Wednesday, 15 May 2019, to Larry Wald, director of the Magnetic Resonance - Physics & Instrumentation Group at the MGH Martinos ...
5 Things You Didn’t Know About David Cohen and MEG
Last week the MGH Martinos Center dedicated its advanced magnetoencephalography (MEG) facility as the David Cohen MEG Laboratory. Cohen—the inventor of MEG, a leader in the field of biomagnetism for more than 50 years, and a Martinos Center faculty member who was instrumental in building and deve...
Publications Updates
May 11, 2020 The presubiculum links incipient amyloid and tau pathology to memory function in older persons Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Neurology. 2020 May 5;94(18):e1916-e1928. doi: 10.1212/WNL.00...
Martinos Responds: ‘Community Help’ Website Brings People Together During a Time of Crisis
As healthcare challenges stemming from the COVID-19 pandemic continue to mount, and patient care and hospital operations schedules grow increasingly busy, many direct care providers are finding ineeds t difficult to keep up with needs at home—grocery shopping, pet care or any number of other resp...
20+20 Vision: 40 Years on the Cutting Edge of Science and Care
We are thrilled to announce the publication of 20+20 Vision: 40 Years on the Cutting Edge of Science and Care, a Martinos Center coffee table book. In 1980, a scrappy group of researchers at Massachusetts General Hospital banded together to explore the potential of a recently introduced techno...
The Center’s Regan Butterfield on Her New Role with SNMMI
Last year, the Martinos Center’s Regan Butterfield was asked to serve as the Education co-chair for the Clinical Trials Network (CTN) for the Society of Nuclear Medicine and Molecular Imaging (SNMMI). In a recent conversation, Butterfield, a research nuclear medicine technologist in the Center, t...
A New Optical Imaging Tool to Visualize Disease Through ‘Multiplexing’
A team of investigators at the MGH Martinos Center for Biomedical Imaging has developed a tool that will allow researchers to measure multiple biological components or processes at the same time, opening up a host of applications, especially related to the study of disease. They describe the tool...
The Possible Role of Glow Sticks—Yes, Glow Sticks—in Treating Alzheimer’s
A new imaging probe that could help to advance therapies for Alzheimer’s disease draws its inspiration from an unlikely source. Research suggests that Alzheimer’s is closely associated with increased levels of ‘reactive oxygen species’ (ROS) in the brain, but actual, in vivo evidence of this h...
Michael Placzek
Dr. Placzek's research focuses on studying human brain diseases with translational molecular imaging - positron emission tomography (PET). Through a multi-faceted approach, his group is working towards a better understanding of the molecular mechanisms involved in brain diseases. Their work is ap...