The overarching aim of Dr. Salat’s work is to understand mechanisms of neural disease and to implement novel approaches to reduce the impact of disease on the brain, cognition and clinical status. Clinically, there are two main clinical foci to his research. At the MGH Martinos Center, he directs the Brain Aging and Dementia Laboratory, with a research focus on understanding systemic and neural mechanisms of age-associated cognitive decline and dementia. A major focus of this work is to understand cerebrovascular contributions to brain aging and dementia. He is also the MGH site Principal Investigator for the Human Connectome Project – Mapping the Human Connectome with Typical Aging multisite effort (Central PI: Van Essen).
Education
PhD in Behavioral Neuroscience, Oregon Health & Science University
Select Publications
1. Bookheimer SY, Salat DH, Terpstra M, Ances BM, Barch DM, Buckner RL, et al. The Lifespan Human Connectome Project in Aging: An overview. Neuroimage. 2019;185:335-48.
2. Sitnikova TA, Hughes JW, Ahlfors SP, Woolrich MW, Salat DH. Short timescale abnormalities in the states of spontaneous synchrony in the functional neural networks in Alzheimer’s disease. Neuroimage Clin. 2018;20:128-52.
3. Robinson ME, Clark DC, Milberg WP, McGlinchey RE, Salat DH. Characterization of Differences in Functional Connectivity Associated with Close-Range Blast Exposure. J Neurotrauma. 2017;34(S1):S53-S61.
Websites
Brain Aging and Dementia (BAnD) Laboratory
The Translational Research Center for TBI and Stress Disorders (TRACTS)